Prognostic value of right pulmonary artery distensibility in dogs with pulmonary hypertension
- Author:
I Ping CHAN
1
;
Min Chieh WENG
;
Tung HSUEH
;
Yun Chang LIN
;
Shiun Long LIN
Author Information
- Publication Type:Original Article
- Keywords: Dogs; pulmonary artery; echocardiography; outcome assessment
- MeSH: Acceleration; Animals; Dogs; Ductus Arteriosus, Patent; Echocardiography; Follow-Up Studies; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Medical Records; Mitral Valve; Pulmonary Artery; Referral and Consultation; Retrospective Studies; Tricuspid Valve Insufficiency
- From:Journal of Veterinary Science 2019;20(4):e34-
- CountryRepublic of Korea
- Language:English
- Abstract: The right pulmonary artery distensibility (RPAD) index has been used in dogs with pulmonary hypertension (PH) caused by heartworm infection, myxomatous mitral valve disease, or patent ductus arteriosus. We hypothesized that this index correlates with the tricuspid regurgitation pressure gradient (TRPG) assessed by echocardiography and could predict survival in dogs with PH secondary to various causes. To assess this hypothesis, the medical records of 200 client-owned dogs at a referral institution were retrospectively reviewed. The RPAD index and the ratios of acceleration time to peak pulmonary artery flow (AT) and to the ejection time of pulmonary artery flow (ET) were recorded for each dog. The owners were contacted for follow-up assessments. The findings indicated that the RPAD index was correlated with the TRPG (R2 = 0. 362, p < 0.001). The survival time was significantly shorter in dogs with an RPAD index ≤ 21% that were followed up for 3 months and in dogs with an RPAD index ≤ 24% that were followed up for 1 year. Thus, the RPAD index was correlated with the TRPG and could predict the clinical outcome in dogs with PH caused by various diseases. This index could be used to evaluate the severity of PH in dogs without tricuspid regurgitation.
