Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
10.4142/jvs.2018.19.4.577
- Author:
Guehwan JANG
1
;
Seong Hee KIM
;
Yoo Jin LEE
;
Seungjoon KIM
;
Du Sik LEE
;
Kyoung Ki LEE
;
Changhee LEE
Author Information
1. Animal Virology Laboratory, School of Life Sciences, BK21 Plus KNU Creative BioResearch Group, Kyungpook National University, Daegu 41566, Korea. changhee@knu.ac.kr
- Publication Type:Brief Communication
- Keywords:
cell culture isolation;
genome analysis;
porcine deltacoronavirus;
virulence
- MeSH:
Cell Culture Techniques;
Diarrhea;
Enteritis;
Korea;
Serial Passage;
Virulence
- From:Journal of Veterinary Science
2018;19(4):577-581
- CountryRepublic of Korea
- Language:English
-
Abstract:
Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.
