Identification and characterization of atypical porcine pestivirus genomes in newborn piglets with congenital tremor in China
10.4142/jvs.2018.19.3.468
- Author:
Hanqin SHEN
1
;
Xiangcong LIU
;
Pengfei ZHANG
;
Lei WANG
;
Yanling LIU
;
Leyi ZHANG
;
Pengshuai LIANG
;
Changxu SONG
Author Information
1. College of Animal Science & National Engineering Center for Swine Breeding Industry, South China Agricultural University, Guangzhou 510642, China. cxsong2004@163.com
- Publication Type:Brief Communication
- Keywords:
atypical porcine pestivirus;
congenital tremor;
virus characterization
- MeSH:
Cerebellum;
China;
Genome;
Humans;
Infant, Newborn;
Open Reading Frames;
Pestivirus;
Tremor;
Viral Load
- From:Journal of Veterinary Science
2018;19(3):468-471
- CountryRepublic of Korea
- Language:English
-
Abstract:
Recently, a novel atypical porcine pestivirus (APPV) in pig was reported. In this study, two APPV strains, APPV-China/GZ01/2016 (GZ01) and APPV-China/GD-SD/2016 (GD-SD), were identified in two newborn piglet herds with congenital tremor from China. The open reading frame of the two strains shared an 83.5% nucleotide identity. Phylogenetically, the APPV strains were placed into two groups: GZ01 belonged to group I and GD-SD belonged to group II. A high viral load was detected in the cerebellum (quantification cycles < 26). Further studies should be carried out to thoroughly elucidate the development of congenital tremors caused by APPV.
