Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea
10.4142/jvs.2018.19.2.309
- Author:
Yong Hyun KIM
1
;
Byung Joo PARK
;
Hee Seop AHN
;
Sang Hoon HAN
;
Hyeon Jeong GO
;
Dong Hwi KIM
;
Joong Bok LEE
;
Seung Yong PARK
;
Chang Seon SONG
;
Sang Won LEE
;
In Soo CHOI
Author Information
1. Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea. ischoi@konkuk.ac.kr
- Publication Type:Brief Communication
- Keywords:
feces;
hepatitis E virus;
swine;
zoonosis
- MeSH:
Agriculture;
Feces;
Genotype;
Hepatitis E virus;
Hepatitis E;
Hepatitis;
Humans;
Korea;
RNA;
Sus scrofa;
Swine
- From:Journal of Veterinary Science
2018;19(2):309-312
- CountryRepublic of Korea
- Language:English
-
Abstract:
Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an important reservoir of these genotypes. A survey of 14 pig farms in Korea revealed HEV RNA in 30 of 148 (20.3%) fecal samples. HEV-3a and HEV-4c subtypes were identified in five pig farms (35.7%) and two pig farms (14.3%), respectively. Phylogenetic analysis indicated that the isolated HEV strains were closely related to previously reported zoonotic strains in Korea. The results of the genetic analysis partially explain the possible source of the zoonotic transmission of HEV to humans in Korea.
