Pathologic and molecular characterization of Streptococcus dysgalactiae subsp. equisimilis infection in neonatal piglets
10.4142/jvs.2018.19.2.313
- Author:
Sang Ik OH
1
;
Jong Wan KIM
;
Ji Youl JUNG
;
Myeongju CHAE
;
Yu Ran LEE
;
Jong Ho KIM
;
ByungJae SO
;
Ha Young KIM
Author Information
1. Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea. kimhy@korea.kr
- Publication Type:Case Report
- Keywords:
Streptococcus dysgalactiae subspecies equisimilis;
microbial sensitivity tests;
multilocus sequence typing;
piglet
- MeSH:
Abscess;
Animals;
Arthritis, Infectious;
Death, Sudden;
Encephalitis;
Heart;
Humans;
Joints;
Kidney;
Microbial Sensitivity Tests;
Multilocus Sequence Typing;
Streptococcus;
Swine;
Virulence
- From:Journal of Veterinary Science
2018;19(2):313-317
- CountryRepublic of Korea
- Language:English
-
Abstract:
Streptococcus dysgalactiae subspecies equisimilis (SDSE) is an emerging pathogen in animals and humans. Herein, we describe two clinical swine cases of SDSE infection presenting with lameness, neurological signs, or sudden death. Pathological examination indicated suppurative arthritis, encephalitis, and multifocal abscesses in kidney and heart. The β-hemolytic colonies obtained from joint samples of each case were identified as SDSE. The two isolates had low minimum inhibitory concentrations for β-lactams, and they presented the same virulence gene profile (slo⁻/sagA⁺/pSTKP8⁺). Molecular analysis by multilocus sequence typing identified the SDSE isolates from cases 1 and 2 as sequence types 315 and 252, respectively.
