Prepubertal growth and single nucleotide polymorphism analysis of the growth hormone gene of low birth weight Holstein calves
10.4142/jvs.2018.19.1.157
- Author:
Younghye RO
1
;
Woojae CHOI
;
Hoyung KIM
;
Hojin JANG
;
Hoseon LEE
;
Yoonseok LEE
;
Danil KIM
Author Information
1. Department of Farm Animal Medicine, College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea. danilkim@snu.ac.kr
- Publication Type:Brief Communication
- Keywords:
Holstein calf;
growth hormone;
low birth weight;
prepubertal growth;
single nucleotide polymorphism
- MeSH:
Adolescent;
Birth Weight;
Body Weight;
Exons;
Genotype;
Growth Hormone;
Humans;
Infant, Low Birth Weight;
Infant, Newborn;
Korea;
Parturition;
Polymorphism, Single Nucleotide;
Puberty
- From:Journal of Veterinary Science
2018;19(1):157-160
- CountryRepublic of Korea
- Language:English
-
Abstract:
Holstein calves weighing less than 20 kg at birth have been noted in Korea. Due to insufficient information, we raised small calves with age-matched normal birth weight Holstein calves and determined body weights before puberty. In addition, 3 single nucleotide polymorphisms (SNPs) of the growth hormone (GH) gene were analyzed. Up to 10 months of age, low birth weight calves were smaller than normal weight calves. In exon 5 of the GH gene, SNP genotype variation was detected in some small calves; however, this did not appear to be the only factor inducing low birth weight and slow growth.
