Time Interval from Intubation to Return of Spontaneous Circulation in Out-of-hospital Cardiac Arrest Patient with Brain Hemorrhage
- Author:
Sumin BAEK
1
;
Euigi JUNG
;
Jonghwan SHIN
;
Hui Jai LEE
;
Se Jong LEE
;
Kyoung Min YOU
;
Kyuseok KIM
;
You Hwan JO
;
Jae Hyuk LEE
;
Joonghee KIM
Author Information
1. Department of Emergency Medicine, Seoul National University Boramae Medical Center, Seoul, Korea. nicedoctor00@gmail.com
- Publication Type:Original Article
- Keywords:
Advanced cardiac life support;
Cardiopulmonary resuscitation;
Intracranial hemorrhages;
Intubation;
Prognosis
- MeSH:
Adult;
Advanced Cardiac Life Support;
Airway Management;
Blood Gas Analysis;
Brain;
Cardiopulmonary Resuscitation;
Female;
Humans;
Intracranial Hemorrhages;
Intubation;
Logistic Models;
Out-of-Hospital Cardiac Arrest;
Potassium;
Prognosis;
Prospective Studies;
Retrospective Studies;
ROC Curve
- From:Journal of the Korean Society of Emergency Medicine
2018;29(1):57-65
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study was conducted to investigate the relationship of time interval from intubation to return of spontaneous circulation (ROSC) in out-of-hospital cardiac arrest (OHCA) patients according to the presence or absence of intracranial hemorrhage (ICH). METHODS: This retrospective study used data from a prospectively collected OHCA registry for patients treated from January 2008 to December 2016. Non-traumatic adult OHCA patients who underwent brain computed tomography were included, while patients who achieved a prehospital ROSC or required advanced airway management were excluded. Utstein variables, initial blood gas analysis, electrolyte levels, and the time interval from intubation to ROSC were used to compare the ICH and non-ICH groups. RESULTS: A total of 448 patients were analyzed. The ICH group was younger and had more females than the non-ICH group. The time interval from intubation to ROSC was significantly shorter in the ICH group than the non-ICH group. The median time and interquartile range were 3 (2 to 7) minutes in the ICH group and 6 (3 to 10) minutes in the non-ICH group. The patient age, gender, potassium level, and time interval from intubation to ROSC were significant variables in the multivariable analysis. In a multivariable logistic regression model that included these variables, the area under the receiver operating characteristic curve was 0.838. CONCLUSION: OHCA patients with ICH achieve ROSC after intubation in a shorter amount of time than those without ICH.