How to Determine P300 Component in Auditory Event Related Potential Brain Topography.
- Author:
Sang Ick HAN
1
;
Yang Whan JEON
Author Information
1. Department of Neuropsychiatry, Our Lady of Mercy Hospital, the Catholic University of Korea, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Global field power measurement(GFPM);
Classical method(CM);
Event related potential(ERP);
P300;
Topography
- MeSH:
Brain*;
Diagnostic and Statistical Manual of Mental Disorders;
Event-Related Potentials, P300*;
Humans;
Schizophrenia
- From:Journal of Korean Neuropsychiatric Association
1998;37(1):174-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTS: This study was designed to make a comparison between methods to determine the components of topographic auditory event related potential P300. METHODS: The subjects were consisted of 44 normal controls and 44 patients with schizophrenia diagnosed by DSM-IV. The topographic auditory event related P300 was recorded in oddball paradigm. The components of P300, including latency, amplitude, and location of maximum amplitude in X-Y coordinates, were analized by computerized EP mapping system. The latency of P300 was determined by both global field power measurement and classic method. RESULTS: There was difference between two groups in latency(DF=1, F=35.28, P= 0.0001) and amplitude(DF=1, F=36.62, P=0.0001), but not in X coordinate(DF=1, F=0.37, P=0.55) and Y coordinate(DF=1, F=2.00, P=0.16). There was no difference between two mothods in latency(DF=1, F=0.04, P=0.85), in amplitude(DF=1, F=0.07, P=0.79), in X coordinate(DF=1, F=0.07, P=0.79), and in Y coordinate(DF=1, F=0.03, P=0.86). CONCLUSION: The results suggested that two methods to determine the components of topographic auditory event related potential P300 should be available for both research and clinical application to date.
