Relationship Between Neurological Degenerative Disorders and a Blood Deficiency Using ki-ketsu-sui Score

Yoshikazu Mizoi; Shinichiro Ueda; Koichiro Tanaka; Koki Chiba; Kazuhiko Nara; Toshimasa Yamamoto

Return

Relationship Between Neurological Degenerative Disorders and a Blood Deficiency Using ki-ketsu-sui Score

VernacularTitle:神経変性疾患と血虚との関連性について
Author: Yoshikazu MIZOI ¹ ; Shinichiro UEDA ² ; Koichiro TANAKA ³ ; Koki CHIBA ³ ; Kazuhiko NARA ³ ; Toshimasa YAMAMOTO ¹
Author Information

1. Department of Neurology, Saitama Medical University, School of Medicine
2. Department of Clinical Research and Quality Management, University of The Ryukyus, Graduate School of Medicine
3. Department of Traditional Medicine, Toho University Omori Medical Center, School of Medicine
Keywords: neurological degenerative disorders; ki-ketsu-sui score; multivariate analysis; blood deficiency; shimotsuto rui
From:Kampo Medicine 2019;70(1):1-7
CountryJapan
Language:Japanese
Abstract: We evaluated body constituents patterns of 74 consecutive patients with neurological degenerative disorders. They comprise Parkinson's disease (n = 38), amyotrophic lateral sclerosis (n = 19), and multiple system atrophy (n = 17). We compared body constituents patterns between them and 149 consecutive patients with other neurological diseases of the same age. We used ki-ketsu-sui scores to evaluate body constituents patterns in all cases. Ki-ketsu-sui scores measure six factors : qi deficiency (kikyo), qi stagnation (kiutsu), qi counterflow (kigyaku), blood deficiency (kekkyo), blood stasis (oketsu), and fluid retention (suitai). As a result of multivariate analysis, neurological degenerative disorders had large weight of blood deficiency, fluid retention and qi stagnation. Their adjusted odds ratios (95% confidence interval) were 3.02 (1.43-6.48), 2.37 (1.13-5.11), 2.33 (1.01-5.44), respectively. Most relevant factor to neurological degenerative disorders was a blood deficiency. Taking into consideration a prescription of “shimotsuto rui” may contribute to alleviate patient's suffering. In addition to subjective symptoms, we need an oriental medicine scale such as pulse, tongue, and abdominal examinations to judge a therapeutic effect of Kampo medicine.