GCN2 deficiency protects mice from denervation-induced skeletal muscle atrophy via inhibiting FoxO3a nuclear translocation.

Author: Yuting GUO ¹ ; Huiwen WANG ² ; Yinglong TANG ² ; Yue WANG ¹ ; Mengqi ZHANG ² ; Zhiguang YANG ² ; Eric NYIRIMIGABO ² ; Bin WEI ² ; Zhongbing LU ³ ; Guangju JI ⁴
Author Information

1. College of Life Science, University of Chinese Academy of Sciences, Beijing, 100049, China.
2. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
3. College of Life Science, University of Chinese Academy of Sciences, Beijing, 100049, China. luzhongbing@ucas.ac.cn.
4. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. gj28@ibp.ac.cn.
Publication Type:Letter
MeSH: Active Transport, Cell Nucleus; Animals; Cell Nucleus; metabolism; Forkhead Box Protein O3; metabolism; Mice; Mice, Knockout; Muscle, Skeletal; metabolism; pathology; Muscular Atrophy; metabolism; pathology; Protein-Serine-Threonine Kinases; deficiency; metabolism
From: Protein & Cell 2018;9(11):966-970
CountryChina
Language:English