BMAL1 functions as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis.
10.1007/s13238-018-0514-y
- Author:
Jian LI
1
;
Sihan LV
1
;
Xinchen QIU
1
;
Jiamin YU
1
;
Junkun JIANG
1
;
Yalan JIN
2
;
Wenxuan GUO
2
;
Ruowei ZHAO
2
;
Zhen-Ning ZHANG
3
;
Chao ZHANG
4
;
Bing LUAN
5
Author Information
1. Department of Endocrinology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
2. Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, China.
3. Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, China. znzhang@tongji.edu.cn.
4. Translational Medical Center for Stem Cell Therapy & Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji University, Shanghai, China. zhangchao@tongji.edu.cn.
5. Department of Endocrinology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China. bluan@tongji.edu.cn.
- Publication Type:Letter
- MeSH:
ARNTL Transcription Factors;
deficiency;
metabolism;
Animals;
Cyclic AMP;
metabolism;
Gluconeogenesis;
Glucose;
biosynthesis;
HEK293 Cells;
Histone Deacetylases;
metabolism;
Humans;
Liver;
metabolism;
Mice;
Mice, Knockout
- From:
Protein & Cell
2018;9(11):976-980
- CountryChina
- Language:English
