The newly emerged SARS-like coronavirus HCoV-EMC also has an "Achilles' heel": current effective inhibitor targeting a 3C-like protease.
10.1007/s13238-013-2841-3
- Author:
Zhilin REN
1
;
Liming YAN
;
Ning ZHANG
;
Yu GUO
;
Cheng YANG
;
Zhiyong LOU
;
Zihe RAO
Author Information
1. College of Pharmacy and State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin 300071, China.
- Publication Type:Journal Article
- MeSH:
Binding Sites;
Cysteine Endopeptidases;
metabolism;
Humans;
Isoxazoles;
chemistry;
pharmacology;
Protease Inhibitors;
chemistry;
metabolism;
pharmacology;
Protein Structure, Tertiary;
Pyrrolidinones;
chemistry;
pharmacology;
Rhinovirus;
drug effects;
SARS Virus;
drug effects;
enzymology;
Severe Acute Respiratory Syndrome;
virology;
Viral Proteins;
antagonists & inhibitors;
metabolism
- From:
Protein & Cell
2013;4(4):248-250
- CountryChina
- Language:English