Cellular models for disease exploring and drug screening.
10.1007/s13238-010-0027-9
- Author:
Zhi-Kun LI
1
;
Qi ZHOU
2
Author Information
1. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
2. State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China. qzhou@ioz.ac.cn.
- Publication Type:Journal Article
- MeSH:
Animals;
Drug Evaluation, Preclinical;
methods;
Humans;
Induced Pluripotent Stem Cells;
cytology;
Models, Biological;
Neurodegenerative Diseases;
therapy
- From:
Protein & Cell
2010;1(4):355-362
- CountryChina
- Language:English
-
Abstract:
The biopharmaceutical industry has been greatly promoted by the application of drug and disease models, including both animal and cellular models. In particular, the emergence of induced pluripotent stem cells (iPSC) makes it possible to create a large number of disease-specific cells in vitro. This review introduces the most widely applied models and their specialties.
