Carbapenem-Resistant Acinetobacter baumannii.
- Author:
Il Kwon BAE
1
;
Seok Hoon JEONG
;
Kyungwon LEE
Author Information
- Publication Type:Review
- Keywords: Acinetobacter baumannii; Carbapenem; Worldwide clone 2
- MeSH: Acinetobacter; Acinetobacter baumannii; Clone Cells; Drug Resistance, Multiple; Imipenem; Korea; Thienamycins
- From:Korean Journal of Clinical Microbiology 2012;15(1):1-8
- CountryRepublic of Korea
- Language:Korean
- Abstract: Clinical isolates of Acinetobacter spp. in Korea exhibit higher antimicrobial resistance rates than in foreign countries and frequently show multi-drug resistance. Approximately 67% (272/405) of Acinetobacter baumannii isolates collected from 19 hospitals in Korea in 2008 exhibited intermediate susceptibility or resistance to imipenem and/or meropenem. The most important mechanisms in acquiring carbapenem resistance in A. baumannii in Korea are production of OXA-23 and overproduction of OXA-51, while that in non-baumannii Acinetobacter is the production of metallo-beta-lactamases. All the carbapenem-resistant A. baumannii isolates were identified as clonal complex 92 and belonged to worldwide clone 2.
