Rab1A mediates proinsulin to insulin conversion in β-cells by maintaining Golgi stability through interactions with golgin-84.
10.1007/s13238-016-0298-x
- Author:
Xiaojing LIU
1
;
Zhenguo WANG
1
;
Ying YANG
1
;
Qingrun LI
1
;
Rong ZENG
1
;
Jiuhong KANG
2
;
Jiarui WU
3
Author Information
1. Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China.
2. Clinical and Translational Research Center of Shanghai First Maternity and Infant Health Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Science and Technology, Tongji University, Shanghai, 200092, China.
3. Key Laboratory of Systems Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China. wujr@sibs.ac.cn.
- Publication Type:Letter
- MeSH:
Animals;
Autoantigens;
genetics;
metabolism;
Cell Line, Tumor;
Golgi Apparatus;
genetics;
metabolism;
Golgi Matrix Proteins;
Insulin-Secreting Cells;
metabolism;
Membrane Proteins;
genetics;
metabolism;
Proinsulin;
genetics;
metabolism;
Rats;
rab1 GTP-Binding Proteins;
genetics;
metabolism
- From:
Protein & Cell
2016;7(9):692-696
- CountryChina
- Language:English
