3-Anhydro-6-hydroxy-ophiobolin A displays high in vitro and in vivo efficacy against influenza A virus infection.

Author: Song WANG ¹ ; Xiaoqin LUO ¹ ; Ruoxiang YAN ¹ ; Quanxin WANG ² ; Qiuyue QI ² ; Xiaojuan CHI ¹ ; Lanlan ZHANG ¹ ; Ziding YU ¹ ; Binxiang CAI ¹ ; Ji-Long CHEN ³ ; Hongwei LIU ⁴
Author Information

1. College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, China.
2. Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China.
3. College of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, 350002, China. chenjl@im.ac.cn.
4. Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, China. liuhw@im.ac.cn.
Publication Type:Letter
MeSH: A549 Cells; Animals; Drug Evaluation, Preclinical; Drug Resistance, Viral; drug effects; Humans; Influenza A virus; metabolism; Mice, Inbred BALB C; Orthomyxoviridae Infections; drug therapy; metabolism; Sesterterpenes; chemistry; pharmacology
From: Protein & Cell 2016;7(11):839-843
CountryChina
Language:English