Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach.
10.1007/s13238-015-0225-6
- Author:
Yuwei BAI
1
;
Shinya TASHIRO
2
;
Satoru NAGATOISHI
2
;
Toru SUZUKI
3
;
Dongke YAN
1
;
Ruihua LIU
1
;
Kouhei TSUMOTO
4
;
Mark BARTLAM
5
;
Tadashi YAMAMOTO
3
Author Information
1. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China.
2. Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan.
3. Cell Signal Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Onna-son, Kunigami, Okinawa, 904-0412, Japan.
4. Medical Proteomics Laboratory, Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan. tsumoto@ims.u-tokyo.ac.jp.
5. State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, 300071, China. bartlam@nankai.edu.cn.
- Publication Type:Letter
- MeSH:
Drug Evaluation, Preclinical;
methods;
Humans;
Intracellular Signaling Peptides and Proteins;
metabolism;
Protein Binding;
drug effects;
Small Molecule Libraries;
chemistry;
pharmacology;
Transcription Factors;
metabolism;
Tumor Suppressor Proteins;
metabolism
- From:
Protein & Cell
2015;6(12):924-928
- CountryChina
- Language:English
