Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression.
10.1007/s13238-016-0261-x
- Author:
Chuu-Yun A WONG
1
;
Haihong JIANG
1
;
Peter W ABEL
1
;
Margaret A SCOFIELD
1
;
Yan XIE
1
;
Taotao WEI
2
;
Yaping TU
3
Author Information
1. Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA.
2. National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. weitt@moon.ibp.ac.cn.
3. Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, 68178, USA. Yat60399@creighton.edu.
- Publication Type:Letter
- MeSH:
Breast Neoplasms;
metabolism;
pathology;
Cell Line, Tumor;
Cell Proliferation;
drug effects;
Down-Regulation;
drug effects;
Female;
Guanine Nucleotide Exchange Factors;
antagonists & inhibitors;
genetics;
metabolism;
Humans;
Indoles;
pharmacology;
MCF-7 Cells;
Maleimides;
pharmacology;
Protein Isoforms;
genetics;
metabolism;
Protein Kinase C;
antagonists & inhibitors;
genetics;
metabolism;
RNA Interference;
RNA, Small Interfering;
metabolism;
Receptor, ErbB-2;
genetics;
metabolism;
Tetradecanoylphorbol Acetate;
toxicity
- From:
Protein & Cell
2016;7(6):445-449
- CountryChina
- Language:English
