Multiple phenotypes in genome-wide genetic mapping studies.
10.1007/s13238-011-1059-5
- Author:
Jurg OTT
1
;
Jing WANG
Author Information
1. Key Laboratory of Mental Health Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China. ottjurg@psych.ac.cn
- Publication Type:Journal Article
- MeSH:
Chromosome Mapping;
Genome-Wide Association Study;
Humans;
Phenotype;
Polymorphism, Single Nucleotide;
Schizophrenia;
genetics
- From:
Protein & Cell
2011;2(7):519-522
- CountryChina
- Language:English
-
Abstract:
For many psychiatric and other traits, diagnoses are based on a number of different criteria or phenotypes. Rather than carrying out genetic analyses on the final diagnosis, it has been suggested that relevant phenotypes should be analyzed directly. We provide an overview of statistical methods for the joint analysis of multiple phenotypes in case-control association studies.