Spikes with short inter-spike intervals in frog retinal ganglion cells are more correlated with their adjacent neurons' activities.
10.1007/s13238-011-1091-5
- Author:
Wen-Zhong LIU
1
;
Ru-Jia YAN
;
Wei JING
;
Hai-Qing GONG
;
Pei-Ji LIANG
Author Information
1. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China.
- Publication Type:Journal Article
- MeSH:
Action Potentials;
Animals;
Computer Simulation;
Darkness;
Electrophysiology;
In Vitro Techniques;
Light;
Patch-Clamp Techniques;
Postsynaptic Potential Summation;
Rana catesbeiana;
physiology;
surgery;
Retina;
physiology;
Retinal Ganglion Cells;
physiology;
Retinal Neurons;
physiology;
Signal Transduction
- From:
Protein & Cell
2011;2(9):764-771
- CountryChina
- Language:English
-
Abstract:
Correlated firings among neurons have been extensively investigated; however, previous studies on retinal ganglion cell (RGC) population activities were mainly based on analyzing the correlated activities between the entire spike trains. In the present study, the correlation properties were explored based on burst-like activities and solitary spikes separately. The results indicate that: (1) burst-like activities were more correlated with other neurons' activities; (2) burst-like spikes correlated with their neighboring neurons represented a smaller receptive field than that of correlated solitary spikes. These results suggest that correlated burst-like spikes should be more efficient in signal transmission, and could encode more detailed spatial information.
