Transcriptional activators and activation mechanisms.
10.1007/s13238-011-1101-7
- Author:
Jun MA
1
Author Information
1. Division of Biomedical Informatics, Division of Developmental Biology, Cincinnati Children's Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA. jun.ma@cchmc.org
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Trans-Activators;
genetics;
metabolism;
Transcription Factors;
genetics;
metabolism;
Transcription, Genetic;
Transcriptional Activation
- From:
Protein & Cell
2011;2(11):879-888
- CountryChina
- Language:English
-
Abstract:
Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.
