The lipid droplet: A conserved cellular organelle.
10.1007/s13238-017-0467-6
- Author:
Congyan ZHANG
1
;
Pingsheng LIU
2
Author Information
1. National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
2. National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. pliu@ibp.ac.cn.
- Publication Type:Journal Article
- Keywords:
conserved organelle;
lipid droplet;
lipid metabolism;
nucleic acid handling
- MeSH:
Animals;
Bacteria;
metabolism;
ultrastructure;
Biological Evolution;
Cholesterol Esters;
metabolism;
Humans;
Lipid Droplets;
chemistry;
metabolism;
ultrastructure;
Lipid Metabolism;
genetics;
Nucleic Acids;
metabolism;
Peptide Initiation Factors;
chemistry;
metabolism;
Protein Binding;
RNA-Binding Proteins;
chemistry;
metabolism;
Ribosome Subunits;
chemistry;
metabolism;
Triglycerides;
metabolism
- From:
Protein & Cell
2017;8(11):796-800
- CountryChina
- Language:English
-
Abstract:
The lipid droplet (LD) is a unique multi-functional organelle that contains a neutral lipid core covered with a phospholipid monolayer membrane. The LDs have been found in almost all organisms from bacteria to humans with similar shape. Several conserved functions of LDs have been revealed by recent studies, including lipid metabolism and trafficking, as well as nucleic acid binding and protection. We summarized these findings and proposed a hypothesis that the LD is a conserved organelle.
