Efficient growth suppression in pancreatic cancer PDX model by fully human anti-mesothelin CAR-T cells.

Author: Hua JIANG ¹ ; Bo SONG ² ; Peng WANG ² ; Bizhi SHI ¹ ; Qixiang LI ³ ; Mingliang FAN ¹ ; Shengmeng DI ¹ ; Jie YANG ⁴ ; Zonghai LI ⁵
Author Information

1. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China.
2. CARsgen Therapeutics, Shanghai, 200231, China.
3. Crown Biosciences, Inc. Science & Technology Innovation Park, Taicang City, 215400, China.
4. Blood Engineering Laboratory, Shanghai Blood Center, Shanghai, 200051, China.
5. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200032, China. Zonghaili@shsmu.edu.cn.
Publication Type:Letter
MeSH: Antineoplastic Agents, Immunological; immunology; pharmacology; Cell Line, Tumor; GPI-Linked Proteins; antagonists & inhibitors; immunology; Humans; Neoplasm Proteins; analysis; immunology; Pancreatic Neoplasms; drug therapy; immunology; pathology
From: Protein & Cell 2017;8(12):926-931
CountryChina
Language:English