Clinical progress of advanced non-small cell lung cancer with epidermal growth factor receptor mutation in China
10.3760/cma.j.issn.1006-9801.2019.08.010
- VernacularTitle:我国表皮生长因子受体突变晚期非小细胞肺癌的临床研究进展
- Author:
Xia SONG
1
;
Hao TIAN
;
Haibo ZHU
;
Ruifen TIAN
Author Information
1. 山西省肿瘤医院呼吸二病区
- Keywords:
Carcinoma;
non-small cell lung;
Receptor;
epidermal growth factor;
Tyrosine kinase inhibitor
- From:
Cancer Research and Clinic
2019;31(8):551-553
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is the most common malignant tumor worldwide. There are more than 700000 new cases diagnosed as lung cancer each year in China, of which 80%-85% are non-small cell lung cancer (NSCLC). The mutation proportion of epidermal growth factor receptor (EGFR) may reach up to 40%-55%. EGFR-tyrosine kinase inhibitor (EGFR-TKI) has become the standard first-line treatment method for advanced NSCLC patients with EGFR mutation. Chinese oncologists have done a large number of clinical studies, providing an important evidence-based medicine proof for treatment of advanced NSCLC with EGFR mutation.