Application of CT image registration in the radiotherapy of uterine cervical neoplasms based on 3D Slicer software
10.3760/cma.j.issn.1006-9801.2019.08.002
- VernacularTitle:基于3DSlicer软件的CT图像配准在子宫颈癌放疗中的应用研究
- Author:
Jiacun XIE
1
;
Mingbo LIU
;
Qian HAN
;
Guangyin WU
;
Liang LI
;
Hengpo LIANG
;
Jianchao LUO
Author Information
1. 河南省人民医院 郑州大学人民医院 河南大学人民医院肿瘤放疗科 450003
- Keywords:
Uterine cervical neoplasms;
Radiotherapy;
3D Slicer software;
Cone-beam computed tomography;
Image registration;
Image-guided radiation therapy
- From:
Cancer Research and Clinic
2019;31(8):510-514
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of CT image and cone beam computed tomography (CBCT) image registration based on 3D Slicer software in image-guided radiotherapy for uterine cervical neoplasms. Methods Based on 3D Slicer software and Slicer RT toolkit, 10 positioning CT images and 50 CBCT images of 10 patients with uterine cervical neoplasms in Henan Provincial People's Hospital between January 2018 and October 2018 had rigid registration and b-spline deformation registration respectively. The dice similarity coefficient (DSC) and Hausdorff distance (HD) of the bladder, rectum, femoral head, spinal cord, and body of CT-CBCT images were compared by using paired t-test before and after the registration. Results Pre-registration, rigid registration and after b-spline deformation registration of CT images and CBCT images, the DSC in the bladder (0.459±0.177, 0.528±0.184, 0.542±0.187, respectively), the rectum (0.564±0.141, 0.632±0.091, 0.684±0.097, respectively), the femoral head (0.695±0.088, 0.833± 0.030, 0.865±0.027, respectively), the spinal cord (0.587±0.119, 0.746±0.085, 0.834±0.032, respectively) and the body surface (0.922±0.013, 0.948±0.011, 0.959±0.009, respectively) showed an increased trend; HD in the bladder (12.8±7.2, 12.2±7.1, 11.7±7.3, respectively), the rectum (5.0±1.8, 4.4±1.2, 3.4±1.2, respectively), the femoral head (3.6±1.2, 1.8±0.5, 1.5 ±0.5, respectively), the spinal cord (4.0 ±1.0, 2.7 ±1.3, 1.8 ±0.5, respectively) and the body surface (6.3±2.1, 5.2±2.0, 4.3±2.0, respectively) showed a decreased trend. The differences of pairwise comparison in the same parts were statistically significant (all P < 0.05). Conclusions Both rigid registration and b-spline deformation registration of CT-CBCT images based on 3D Slicer softwarecan improve the radiotherapy accuracy of uterine cervical neoplasms, and b-spline deformation registration has more significant advantages.
