Progress of possible role of RP11-23J9.4-miRNA-15a-axis inhibiting factor 2-Wnt pathway in thyroid carcinoma

VernacularTitle:RP11-23J9.4-miRNA-15a-体轴发育抑制因子2-Wnt通路在甲状腺癌中可能作用的研究进展
Author: Lili ZHONG ¹ ; Tiezhu MAO ; Yuechen ZHAO ; Yinlong ZHAO
Author Information

1. 吉林省重大疾病分子与化学遗传学重点实验室吉林大学第二医院研究中心
Keywords: Thyroid neoplasms; Axis inhibiting factor 2; Long chain non-coding; RP11-23J9.4; microRNA-15a
From: Cancer Research and Clinic 2019;31(7):496-500
CountryChina
Language:Chinese
Abstract: The occurrence of thyroid gland is easily affected by iodine deficiency, the enzyme defect, drugs, autoimmune and other factors. The increased incidence of thyroid cancer year by year has threatened the health of the human, which requires to study thyroid gland cancer invasion and metastasis, investigate the molecular mechanism of cancer metastasis, search the differential molecular expression gene, predict the metastatic biomarkers and the intervening treatment target molecule, in order to improve the cure rate and the survival rate. This paper reviews the possible role of long chain non-coding RP11-23J9.4-miRNA-15a-axis inhibiting factor 2-Wnt pathway in the occurrence, development and dedifferentiation of thyroid cancer.