Progress of cancer radiotherapy combined with immunotherapy
10.3760/cma.j.issn.1006-9801.2019.07.015
- VernacularTitle:肿瘤放疗与免疫治疗联合应用的研究进展
- Author:
Shenglan HUANG
1
;
Weirong YAO
;
Huiping WAN
Author Information
1. 江西省人民医院肿瘤科
- Keywords:
Neoplasms;
Immunotherapy;
Radiotherapy
- From:
Cancer Research and Clinic
2019;31(7):492-496
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy can improve the local control rate of the tumors by destructing the tumor cells within the radiation field, can reduce the distant spread by activating the body 's anti-tumor immune response through various mechanisms, and also can exert systemic anti-tumor effect synergistically assisted by immunotherapy. As a new combination therapy, a large number of studies have found that local radiotherapy combined with different immunotherapy can benefit the survival of cancer patients. The optimal efficacy is closely related to the appropriate radiotherapy dose, segmentation model and combined timing. This paper discusses the effects of radiotherapy on the immune system, the related basic and clinical researches of radiotherapy and immunotherapy, and the better way to make the combination effectively.