Efficacy and safety of electroacupuncture for perimenopausal insomnia: a randomized controlled trial
- VernacularTitle:电针干预围绝经期失眠的疗效与安全性随机对照研究
- Author:
Fei-Yi ZHAO
;
Hai-Xia YAN
;
Ying-Xia ZHAO
;
Si-Han CHEN
;
Hong XU
- Keywords:
Acupuncture Therapy;
Electroacupuncture;
Insomnia;
Perimenopause;
Climacteric;
Acupuncture Medication Combined;
Randomized Controlled Trial
- From:
Journal of Acupuncture and Tuina Science
2019;17(3):188-195
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effectiveness and safety of electroacupuncture (EA) plus Luohua Anshen oral liquid for patients with perimenopausal insomnia. Methods: A total of 66 participants who met the inclusion criteria were enrolled in the randomized controlled trial and allocated to a treatment group and a control group at a ratio of 1:1, with 33 cases in each group. Both groups were given Luohua Anshen oral liquid as a basic treatment. The treatment group was additionally given EA every other day, three times a week. Both groups were treated for four weeks and a four-week follow-up was conducted. The scores of Pittsburgh sleep quality index (PSQI), Kupperman index (KI) and traditional Chinese medicine sleep syndrome scale (TCMSSS) were recorded at pre- and post-treatment, and at the follow-up. Meanwhile, adverse effects were monitored and recorded. Results: After four-week treatment, the global scores of PSQI, KI and TCMSSS in both groups declined significantly (all P<0.05), and the decreases in the treatment group were more significant than those in the control group (allP<0.05). The global scores of PSQI, KI and TCMSSS in both groups at the follow-up visit were significantly different from the corresponding baseline (allP<0.05), while insignificantly different from those assessed at post-treatment (allP>0.05). The total effective rate was 93.9％ in the treatment group, significantly higher than 72.2％ in the control group (P<0.05). No significant adverse event was reported in this trial excepted one patient experienced slight dizziness in the first acupuncture treatment. Conclusion: EA plus Luohua Anshen oral liquid is safe for perimenopausal insomnia with satisfactory short- and long-term effectiveness, and it shows certain advantage compared with using Luohua Anshen oral liquid alone.
