The applications and prospects of non-coding RNAs in the diagnosis and treatment of heart failure
10.3760/cma.j.issn.1009-8158.2019.08.006
- VernacularTitle:非编码RNA在心力衰竭诊疗中的应用及展望
- Author:
Guibo SONG
1
;
Yong DUAN
Author Information
1. 昆明医科大学第一附属医院医学检验科
- Keywords:
Heart failure;
RNA;
untranslated;
microRNAs;
RNA;
long noncoding;
Biomarkers
- From:
Chinese Journal of Laboratory Medicine
2019;42(8):613-617
- CountryChina
- Language:Chinese
-
Abstract:
Heart failure (HF) is a severe or advanced stage of heart disease with high mortality and readmission rates. The detection of biomarkers plays an important role in the diagnosis, treatment and clinical management of HF. In addition to the traditional biomarkers, the non-coding RNA markers such as miRNA, circRNA, and lncRNA have also shown better future applications in the diagnosis and differential diagnosis of HF, the severity and prognosis assessment, the risk assessment of cardiovascular events after discharge in patients with HF. These biomarkers will also contribute to personalized clinical management of HF.