Attention to plant sterols: a novel risk factor for residual risk assessment of atherosclerotic cardiovascular disease
10.3760/cma.j.issn.1009-8158.2019.08.005
- VernacularTitle:关注植物固醇作为动脉粥样硬化性心血管病残余风险评估新的危险因素
- Author:
Luya WANG
1
;
Ya YANG
;
Shiwei YANG
;
Yujie ZHOU
Author Information
1. 首都医科大学附属北京安贞医院北京市心肺血管疾病研究所动脉硬化研究室
- Keywords:
Cardiovascular disease;
Atherosclerosis;
Phytosterols;
Risk assessment
- From:
Chinese Journal of Laboratory Medicine
2019;42(8):607-612
- CountryChina
- Language:Chinese
-
Abstract:
Plant sterols are a class of compounds naturally produced by plants and structurally similar to cholesterol. For human, plant sterols can only be obtained from food and cannot be utilized directly. With the development of gas chromatography technology and in-depth research on the molecular mechanisms of rare diseases, plant sterols have been found to play important roles in atherosclerotic cardiovascular disease (ASCVD)and become a residual risk factor after statin therapy. As a novel metabolic marker, plant sterols can reflect steady state the imbalance of the cholesterol and the increase of the cholesterol absorption within the human body, and is expected to become a new risk factor for ASCVD residual risk assessment.
