Diagnostic performance of confocal scanning laser ophthalmoscope imaging and compared with color fundus camera in retinal pigment epithelial detachment of polypoidal choroidal vasculopathy
10.3760/cma.j.issn.1005-1015.2019.04.007
- VernacularTitle:共聚焦激光扫描检眼镜与眼底彩色照相对息肉样脉络膜血管病变中视网膜色素上皮脱离的检出比较
- Author:
Yanjiao HUO
1
;
Lihong YANG
;
Yan GUO
;
Wenbin WEI
Author Information
1. 首都医科大学附属北京同仁医院北京同仁眼科中心眼内肿瘤诊治研究北京市重点实验室北京市眼科学与视觉科学重点实验室 100730
- Keywords:
Choroid diseases;
Retinal pigment epithelial detachment;
Confocal scanning laser ophthalmoscope;
Color fundus camera
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(4):348-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe confocal scanning laser ophthalmoscope (cSLO) based retinal imaging and color fundus camera in pigment epithelial detachment (PED) of polypoidal choroidal vasculopathy (PCV).Methods PED of 30 patients (32 eyes) were recruited from June 2016 to June 2017 in the Beijing Tongren Hospital who were detected in high-definition OCT (HD-OCT) and diagnosed as PCV by FFA and ICGA.There were 16 males (17 eyes) and 14 females (15 eyes);aged from 50-83 years,with the mean age of 66.59 years.The photographs of ocular fundus including color fundus camera,cSLO imaging,HD-OCT,FFA and ICGA were analyzed.Multimodal imaging results were regarded as gold standard.Sensitivity and specificity were calculated in serous and hemorrhagic PED diagnosis using color fundus camera and cSLO imaging.The positive number of PED was used to compare between two modes fundus imaging by using x2 test.Results Twenty serous PED eyes,3 hemorrhagic PED eyes and 9 serous/hemorrhagic PED eyes were determined using multimodal imaging.The sensitivity and specificity of color fundus camera were 45% and 100% in detecting serous PED and 100% and 91% in detecting hemorrhagic PED.The sensitivity and specificity of cSLO imaging were 83% and 100% in detecting serous PED and 50% and 86% in detecting hemorrhagic PED.The positive number of serous PED in cSLO imaging was significantly higher than color fundus camera (x2=7.752,P=0.011).The positive number of hemorrhagic PED in cSLO imaging shows no obvious difference compared with color fundus camera (x2=1.164,P=0.419).Conclusion The sensitivity and positive number of detecting serous PED with PCV in cSLO fundus imaging were higher than the color fundus camera technology.