The clinical and multimodal imaging characteristics of paracentral acute middle maculopathy
10.3760/cma.j.issn.1005-1015.2019.04.002
- VernacularTitle:急性黄斑旁中心中层视网膜病变患眼临床特征及多模式影像特征观察
- Author:
Mengyang LI
1
;
Tong QIAN
;
Xiaoxin LI
;
Guosheng SUN
;
Jie HU
;
Zongyi WANG
;
Mingwei ZHAO
;
Jinfeng QU
Author Information
1. 北京大学人民医院眼视光中心、眼科眼病与视光医学研究所视网膜脉络膜疾病诊治研究北京市重点实验室北京大学医学部眼视光学院 100044
- Keywords:
Tomography,optical coherence;
Regional blood flow;
Paracentral acute middle maculopathy;
Multimodal imaging characteristics
- From:
Chinese Journal of Ocular Fundus Diseases
2019;35(4):322-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical and multimodel imaging characteristics ofparacentral acute middle maculopathy (PAMM).Methods Retrospective case series study.From January 2014 to August 2018,12 eyes of 12 patients with PAMM diagnosed in Department of Ophthalmology,Peking University People's Hospital,were included in this study.There were 9 males and 3 females,with the mean age of 57 years.All patients were referred for sudden impaired vision,with or without paracentral scotoma.The patients underwent BCVA,slit lamp examination,fundus photography,FFA and OCT.Simultaneously,OCT angiography (OCTA) was performed in 10 eyes,visual field was performed in 5 eyes,near infrared fundus photography was performed in 1 eye.Clinical and multimodal imaging findings were reviewed and analyzed.Results Among 12 eyes,there were 5 eyes with BCVA 0.05-≤0.1,4 eyes with BCVA 0.3-0.5,3 eyes with BCVA 0.6-1.0.There were 1 eye with central rentinal artery obstruction (CRAO),7 eyes with branch retinal artery obstruction (BRAO).Among them,BRAO with central retinal vein occlusion (CRVO) in 1 eye,with non-arteritic anterior ischemic optic neuropathy in 1 eye,with diabetic retinopathy in 1 eye;old BRAO in 3 eyes;pure BRAO in 1 eye.There were 4 eyes with pure CRVO,including 3 eyes with ischemic CRVO.All eyes demonstrated hyperreflective lesions at the level of the inner nuclear layer and/or outer plexus layer on OCT.En face OCT highlighted the areas with hyperreflectivity corresponding to these lesions.OCTA demonstrated significant deep capillary dropout,abnormal morphology and enlargement of foveal avascular zone.Conclusion Hyperreflective band-like lesions at the level of the inner nuclear layer on OCT and middle retinal perivascular hyperreflectivity on en face scan are characteristic in PAMM.
