Follow-up study on improvement of vascular patency rate of vein bypass graft after coronary artery bypass grafting with medical chemical external stent
10.3760/cma.j.issn.1001-4497.2019.06.009
- VernacularTitle:医用化学胶外支架改善冠状动脉旁路移植术后静脉旁路移植血管通畅率的随访研究
- Author:
Longsheng DAI
1
;
Mingxin GAO
;
Wenyuan YU
;
Bo LI
;
Chengxiong GU
;
Yang YU
Author Information
1. 首都医科大学附属北京安贞医院 100029
- Keywords:
Medical chemical glue;
External stent;
Vein bypass graft;
Restenosis;
Coronary artery by-pass grafting
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2019;35(6):357-360
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and clinical significance of medical chemical glue as an external stent in improving the fluency rate of venous bypass graft after coronary artery bypass grafting .Methods Randomly selected 200 pa-tients from April 2010 to December 2016 included who were underwent coronary artery bypass grafting in Beijing Anzhen Hospi-tal.All patients had different degrees of angina , and coronary angiography showed multi-branches artery lesion.They were ran-domly divided into two groups, 100 in each group.Spray gel group: coronary artery bypass grafting simultaneously spraying medical chemical glue on the surface of the bridge vessel.Unsprayed gel group:simple coronary artery bypass grafting.All 200 patients were followed up in June 2018.The follow-up content mainly included: recent recurrence of angina pectoris, recent echocardiography and electrocardiogram report, coronary CTA or coronary angiography results, and current living conditions. The data obtained were collectively summarized and compared .Results The follow-up rate was 96％ in the sprayed group, and 92％ in the unsprayed group.Compared with the unsprayed group , the incidence of chest pain and angina pectoris was significantly lower in the sprayed group(23.96％ vs.40.22％, P<0.05), the venous occlusion rate of the vein bypass graft in the sprayed group was significantly lower(29.17％ vs.55.43％, P<0.01), the probability of death due to cardiac causes in the sprayed group was significant decrease(1.04％ vs.6.52％, P<0.05), the number of patients with the main adverse cardiac and cerebral events(MACCE) in the sprayed group was significantly lower(9.38％ vs.21.74％, P<0.01), all with statistically significant differences .The number of patients with heart failure and recurrent myocardial infarction was lower in the sprayed group, but there were no statistically significant differences .Conclusion Medical chemical glue as an external stent does play a role in improving the venous patency rate after coronary artery bypass grafting , and it is reliable for the preven-tion and treatment of vein bypass vascular stenosis after coronary artery bypass grafting .
