Recent advances in relationship of Fusobacterium nucleatum to intestinal immunity
10.3760/cma.j.issn.0254-5101.2019.07.012
- VernacularTitle:具核梭杆菌与肠道免疫相关性研究进展
- Author:
Yongyu CHEN
1
;
Yan CHEN
;
Weiguo DONG
Author Information
1. 武汉大学人民医院消化内科 430060
- Keywords:
Fusobacterium nucleatum;
Fusobacterium nucleatum-associated intestinal disease;
In-testinal immunity
- From:
Chinese Journal of Microbiology and Immunology
2019;39(7):558-562
- CountryChina
- Language:Chinese
-
Abstract:
Gut microbial ecosystem is closely related to the immune system and influences human health. Fusobacterium nucleatum ( F. nucleatum) is one of the species of great concern. Increasing evidence shows that F. nucleatum promotes intestinal inflammation and influences the tumor-associated immune micro-environment. This review focused on the recent progress in the influence of F. nucleatum on intestinal immu-nity and the pathogenesis of intestinal diseases in order to discover the immune mechanism of F. nucleatum-associated intestinal diseases and find new therapeutic targets for immunotherapy.
