Advances in the effectiveness of rotavirus vaccines and its influencing factors
10.3760/cma.j.issn.0254-5101.2019.06.011
- VernacularTitle:轮状病毒疫苗有效性及其影响因素研究进展
- Author:
Jinxia WANG
1
;
Xuanyi WANG
Author Information
1. 复旦大学生物医学研究院
- Keywords:
Rotavirus;
Vaccine;
Effectiveness
- From:
Chinese Journal of Microbiology and Immunology
2019;39(6):472-484
- CountryChina
- Language:Chinese
-
Abstract:
Rotavirus is the leading cause of acute gastroenteritis in children, and vaccines are the most effective measure to control rotavirus diarrhea. Currently, two vaccines, namely Rotarix and RotaTeq, are widely used worldwide. In addition, several vaccines are licensed in some countries. This review summa-rized the effectiveness of licensed rotavirus vaccines and the potential factors which might affect the effective-ness of these vaccines. In addition, progress in novel vaccine candidates in development was also included in this review.