Botulinum toxin type A injection in the treatment of dystonia after a stroke
10.3760/cma.j.issn.0254-1424.2019.08.005
- VernacularTitle:A型肉毒毒素注射治疗卒中后肌张力障碍的临床观察
- Author:
Weisheng ZHUANG
1
;
Wanyue LI
;
Baoyan QIAN
;
Xiguo CAI
;
Zhenzhen GUO
;
Heng WANG
;
Ying ZHANG
Author Information
1. 河南省人民医院康复医学科
- Keywords:
Stroke;
Dystonia;
Botulinum toxin A;
Benzhexol
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2019;41(8):579-583
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of injecting botulinum toxin type A on muscle tension,disability level and ability in the activities of daily living in patients with post-stroke dystonia.Methods Thirty-two patients with post-stroke dystonia were divided into an observation group (n =16) and a control group (n =15).The patients in the observation group were injected with 200-600 U of botulinum toxin type A in the relevant muscles,while the patients in the control group were given 12 mg diphenhydrazole hydrochloride tablets orally.Before and 2,6 and 12 weeks after the treatment,spasticity,disability and daily living ability were evaluated in both groups using the modified Ashworth scale (MAS),a disability assessment scale (DAS) and the modified Barthel index (MBI).Results After the treatment,the average MAS,DAS and MBI scores of both groups were significantly better than before the treatment.And the average MAS,DAS and MBI scores of the observation group were significantly better than those of the control group.Conclusion Botulinum toxin A injection can significantly improve dystonia and relieve disability among stroke survivors.
