The application prospect of transcranial magnetic stimulation in the pathophysiology research and treatment of Parkinson's disease
10.3760/cma.j.issn.1006-7876.2019.08.001
- VernacularTitle:经颅磁刺激在帕金森病病理生理学研究及治疗中的应用
- Author:
Lijuan WANG
1
;
Yihui QIU
;
Kun NIE
;
Yuyuan GAO
Author Information
1. 广东省人民医院(广东省医学科学院)神经科
- Keywords:
Parkinson disease;
Transcranial magnetic stimulation;
Pathology;
Physiology;
Treatment outcome
- From:
Chinese Journal of Neurology
2019;52(8):601-606
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease (PD) is a common neurodegenerative disease,pathogenesis of which is extremely complex.To explore the potential pathophysiological mechanism of PD and find effective treatment methods to improve symptoms,modify the disease and delay the progression are the major problems to be solved urgently.Studies have shown that transcranial magnetic stimulation (TMS) has a broad clinical application prospect,which might help clinicians to explore the pathophysiological mechanism of PD and provide new ideas for exploring new targets for diagnosis and treatment in the future.Meanwhile,TMS might play important roles in the treatment of PD motor and non-motor symptoms through enhancing synaptic plasticity,protecting monoamine neurons,increasing the monoamine neurotransmitter level in the brain,and adjusting the brain network with dysfunction.
