Intraoperative frozen pathological diagnosis in radical resection of hilar cholangiocarcinoma
10.3670.cma.j.issn.1007-631X.2019.08.003
- VernacularTitle:冰冻病理诊断在肝门部胆管癌根治术中的应用
- Author:
Bing PAN
1
;
Shaocheng LYU
;
Xin ZHAO
;
Zhihua ZHANG
;
Ping LI
;
Lixin LI
;
Ren LANG
;
Qiang HE
Author Information
1. 首都医科大学附属北京朝阳医院肝胆外科北京市器官移植中心 100020
- Keywords:
Bile duct neoplasms;
Pothology,clinical
- From:
Chinese Journal of General Surgery
2019;34(8):656-658
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate rapid frozen pathology in the operation of hilar cholangiocarcinoma.Methods Clinical data of 49 patients of hilar cholangiocarcinoma undergoing surgical treatment were analyzed retrospectively from Jan 2011 to Dec 2017 at Department of Hepatobiliary Surgery,Beijing Chaoyang Hospital Affiliated to Capital Medical University to evaluate rapid frozen pathology on operative strategy of hilar cholangiocarcinoma and the prognosis of patients.Results All patients with hilar cholangiocarcinoma underwent intraoperative frozen pathological examination.5 patients adjusted the operation approach because of the discrepancy between frozen pathological examination and preoperative imaging results.47 intraoperative frozen pathological results were consistent with postoperative pathological diagnosis,and the accuracy rate was 95.9％,sensitivity 90％,specificity 97.4％,false positive rate 2.6％,false negative rate 10％.Frozen section margin negative patients had significantly longer survival time(P ＜ 0.05).Conclusions Intraoperative frozen pathological examination can guide the operation approach,greatly improve the resection rate of R0 and the prognosis of patients.
