Malignant solitary fibrous tumor: a clinicopathological study on 11 cases
10.3760/cma.j.issn.1007-631X.2019.06.007
- VernacularTitle:恶性孤立性纤维性肿瘤11例临床诊治分析
- Author:
Songlin AN
1
;
Fengcai YAN
;
Aimin ZHAO
Author Information
1. 首都医科大学附属北京世纪坛医院腹膜肿瘤外科 100038
- Keywords:
Solitary fibrous tumors;
Disease-free survival;
Pathology,clinical
- From:
Chinese Journal of General Surgery
2019;34(6):498-501
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical features,pathological characters,treatment and prognosis of patients with malignant solitary fibrous tumor (MSFT).Methods Retrospective analysis was made on the clinical data of 11 MSFT patients undergoing surgical resection in Beijing Shijitan Hospital from Jan 2010 to Dec 2017.Overall survival (OS) and disease-free survival (DFS) were assessed using Kaplan-Meier methods.Results One patient died of duodenal fistula within a month after surgery,and the other 10 patients recovered with no severe complications.Immunohistochemically,the tumor cells are all positive for CD34 (11/11) and vimentin (10/10) in a different degree.The median OS and DFS for the 10 patients were 49 and 26 months respectively.The 1-,3-,and 5-year OS rates were 89％,56％,42％ respectively.The 1-,3-,and 5-year DFS rates were 79％,34％,23％ respectively.Conclusion MSFT is a malignancy with high recurrence rate.Tumor recurrence was the main cause of death for patients with MSFT.
