Clinical biological characteristics of metastatic carcinoma of the thyroid: a report of 30 cases
10.3760/cma.j.issn.1007-631X.2019.06.005
- VernacularTitle:30例甲状腺转移癌的临床生物学特征及诊疗体会
- Author:
Yu WU
1
;
Xiangrui MENG
;
Linfei HU
;
Xiukun HOU
;
Jingtai ZHI
;
Jun ZHANG
;
Huijuan WANG
;
Hui LIU
;
Xiangqian ZHENG
;
Ming GAO
Author Information
1. 福建省肿瘤医院福建医科大学附属肿瘤医院头颈外科
- Keywords:
Neoplasms metastasis;
Thyroid;
Prognosis
- From:
Chinese Journal of General Surgery
2019;34(6):489-492
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To study the clinical characteristics,diagnosis,treatment and prognosis of cancer metastases to the thyroid gland.Methods At Tianjin Medical University Cancer Hospital,from 1980 to 2016 30 patients were identified with a metastatic malignant tumor of the thyroid gland.Results Primary tumor sites were in the esophagus (26.7%),lung (16.7%),and kidney (13.3%).The median age at discovery of thyroid metastasis was 56 years old.The time lapse ranged from 0 to 108 months.There were 18 patients with metachronous metastasis with median survival of 36 months,12 patients were with synchronous metastasis,and the median survival was 8 months (P < 0.01).20 patients were treated with thyroid surgery,and of which 15 patients were given post-op radiotherapy and chemotherapy.Patients who underwent thyroid resection had a median survival of 15 months,while that was 8 months in those without thyoid surgery (P < 0.01).Conclusions Metastases to the thyroid gland is a rare clinical phenomenon,the prognosis of patients is mainly related to the biological behavior of primary tumors,but surgical resection and combined treatment can increase the survival rate.