Transcatheter arterial chemoembolization and portal vein embolization prior to scheduled laparoscopic right hemihepatectomy for patients with large liver tumor
10.3760/cma.j.issn.1007-631X.2019.05.012
- VernacularTitle:TACE联合PVE行腹腔镜右半肝切除术在巨大肝癌治疗中的应用
- Author:
Jie LIU
1
;
Chengwu ZHANG
;
Yuhua ZHANG
;
Jungang ZHANG
;
Weiding WU
;
Zhiming HU
Author Information
1. 浙江省人民医院肝胆胰外科及微创外科 310014
- Keywords:
Liver neoplasms;
Hepatectomy;
Chemoembolization,therapeutic
- From:
Chinese Journal of General Surgery
2019;34(5):421-424
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of transcatheter arterial chemoembolization (TACE) combined with portal vein embolization (PVE) prior to laparoscopic right hemihepatectomy (LRH) in the treatment of large liver tumor.Methods A retrospective study was conducted based on the clinical data of 8 patients with large liver tumor undergoing PVE combined with TACE before scheduled LRH,with 4 cases receiving simultaneous TACE + PVE and the other 4 cases doing sequential TACE + PVE.Results The interval between TACE and PVE was 14-29 d in sequential group,and the interval between PVE and surgery was 13-30 d.Patients in simultaneous treatment group encountered more prominent elevation of transaminase after PVE and TACE,but they recovered to comparable levels with the sequential group before surgery.The average standard future liver remnant (sFLR) increased from 35.3％ ± 4.9％ to 48.7％ ± 5.1％ before surgery.LRH was performed sucessfully in all patients with no conversion and perioperative death.Complications occurred in 2 cases,including pulmonary infection and bile leakage.The median hospital stay was 36 days.All patients were survival in the 25 months median follow up time including 2 recurrence cases.Conclusions TACE combined with PVE prior to LRH in the treatment of large liver tumor is safe and feasible.
