Seven cases of infant lichen scrofulosorum related to bacillus Calmette-Guérin vaccination
10.3760/cma.j.issn.0412-4030.2019.08.004
- VernacularTitle:与卡介苗接种相关的婴儿瘰疬性苔藓七例
- Author:
Yangyang LIN
1
;
Zekun GONG
;
Li ZHAO
;
Qinfeng LI
Author Information
1. 天津市儿童医院皮肤科 300134
- Keywords:
Tuberculosis,cutaneous;
Infant;
Skin manifestations;
Pathologic processes;
Lichen scrofulosorum
- From:
Chinese Journal of Dermatology
2019;52(8):533-536
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the etiology,clinical manifestations,diagnosis and outcomes of lichen scrofulosorum (LS).Methods Clinical data collected from 7 infants with LS,who visited Department of Dermatology,Tianjin Children's Hospital between 2010 and 2018,were analyzed retrospectively,and the etiology,clinical manifestations,diagnosis,development and outcomes of LS were investigated.Results All the 7 infants developed LS after bacillus Calmette-Guérin (BCG)vaccination,and the clinical manifestations of LS were reddish or hazel papules mainly distributed on the trunk with small scales attached to the surface.No abnormal laboratory examination results were observed.Histopathological examination showed granuloma in the dennis.Without any treatment,all rashes of the 7 patients disappeared within 6 months,and no scar or hyperpigmentation remained.Conclusions Infant LS usually appears 2-3 months after BCG vaccination,clinically presents as papules mostly on the trunk,pathologically characterized as granuloma in the dermis,and can heal spontaneously.
