Single-cell RNA sequencing and its application in dermatology
10.3760/cma.j.issn.0412-4030.2019.07.015
- VernacularTitle:单细胞RNA测序技术及其在皮肤病学研究中的应用
- Author:
Ronghui ZHU
1
;
Wei LI
Author Information
1. 复旦大学附属华山医院皮肤科
- Keywords:
Sequence analysis,RNA;
Single-cell RNA sequencing;
High-throughput RNA sequencing;
Dermatology;
Genetic heterogeneity
- From:
Chinese Journal of Dermatology
2019;52(7):506-509
- CountryChina
- Language:Chinese
-
Abstract:
Single-cell RNA sequencing is a method for transcriptome profiling at the single-cell level,and is a hotspot technology in the field of biological research currently.Compared with the common high-throughput RNA sequencing,single-cell RNA sequencing can distinguish the biological differences between single cells,and identify rare cell populations and subpopulations.This review mainly describes the single-cell RNA sequencing method,summarizes current application of this technique in the field of dermatology,and discusses limitations and prospects of this technique.
