The Methicillin-Resistance Rate of Staphylococcus aureus Isolatd from Anterior Nares of Healthy Adults in the Community.
- Author:
Hong Bin KIM
1
;
Dong Hyeon SHIN
;
Kyung Un PARK
;
Myoung Don OH
;
Eui Chong KIM
;
Kang Won CHOE
Author Information
1. Departments of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Methicillin-resistant Stap hylococcus aureus;
Surveillance;
Community
- MeSH:
Adult*;
Diffusion;
Humans;
Korea;
Mass Screening;
Methicillin Resistance;
Methicillin-Resistant Staphylococcus aureus;
Oxacillin;
Polymerase Chain Reaction;
Prevalence;
Risk Factors;
Staphylococcus aureus*;
Staphylococcus*
- From:Korean Journal of Infectious Diseases
1998;30(6):527-531
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: About 80% of nosocomial Stap hylococcus aureus isolates demonstrate methicillin resistance in Korea. To assess the prevalence of methicillin- resistant S. aureus (MRSA) in the community, we screened the nasal S. aureus isolates from healthy adults. METHODS: Nasal cultures were collected from healthy adults without known risk factors for acquisition of MRSA. Antimicrobial susceptibility of S. aureus isolates against oxacillin were determined using the E- test and the disk diffusion method. Methicillin resistant isolates were tested for the mecA gene by polymerase chain reaction. RESULTS: Total 689 subjects were studied. The point prevalence of S. aureus was 33% (227/689). Sixteen isolates of S. aureus grew on the MRSA screening plates(MAO), of which 5(2.2%) were resistant to oxacillin and positive for the mecA gene. CONCLUSION: Less than 5% (95% CI; 1 ~5%) of the nasal S. aureus isolates in the community were methicillin-resistant.
