Predicting the risk of muscle-invasive bladder cancer using vesical imaging-reporting and data system
10.3760/cma.j.issn.1000-6702.2019.07.005
- VernacularTitle:膀胱影像报告和数据系统对肌层浸润性膀胱癌的预测价值研究
- Author:
Henglong HU
1
;
Boya LI
;
Xiaoyan MENG
;
Lei CUI
;
Cong LI
;
Zhihua WANG
;
Zheng LIU
;
Xiaolin GUO
;
Yanchun WANG
;
Zhen LI
;
Shaogang WANG
Author Information
1. 华中科技大学同济医学院附属同济医院泌尿外科
- Keywords:
Vesical imaging-reporting and data system;
Muscle invasive bladder cancer;
Non-muscle invasive bladder cancer;
Multiparametric magnetic resonance imaging
- From:
Chinese Journal of Urology
2019;40(7):503-506
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy and clinical significance of the vesical imagingreporting and data system (Ⅵ-RADS) in predicting muscle-invasive bladder cancer (MIBC).Methods The data of 59 bladder cancer patients who underwent multiparametric magnetic resonance imaging and surgery between 2014 March and 2019 May were retrospectively analyzed,which includes 51 males and 8 females,aged 36-82 years old,with a median age of 62 years old.According to the scoring methods specified by Ⅵ-RADS,radiologists read and scored all mpMRIs including T2-weighted imaging (T2WI),diffusion-weighted imaging(DWI),and dynamic contrast enhancement MRI(DCE-MRI) of all the included patients.And then the Ⅵ-RADS were compared with pathological diagnosis.Proportions of MIBC in each score category were calculated,and ROC curve was plotted and the area under the curve (AUC) was estimated to assess the sensitivity and specificity of Ⅵ-RADS in diagnosing MIBC.Results The number of patients in Ⅵ-RADS score category 1 to 5 were 12,28,2,15 and 2,respectively.And there were 0,2 (7.4％),1 (50.0％),13 (81.3 ％),2 (100.0％) MIBC patients in each score category,respectively.When Ⅵ-RADS ≥3 was used to define MIBC,it came to the largest Youden's Index(0.7913),with an AUC of 0.924.And the sensitivity and specificity were 88.9％ and 90.2％,respectively.Conclusions Ⅵ-RADS has high accuracy in predicting MIBC,and it is worthy of application and verification in further clinical practice.The urologists should be highly alert to the existence of MIBC when Ⅵ-RADS ≥3.
