Characteristics of serum lipid levels in 899 centenarians of Hainan
10.3760/cma.j.issn.0254-9026.2019.06.022
- VernacularTitle:海南省899例百岁老人血脂状况研究
- Author:
Yan LI
1
;
Yali ZHAO
;
Liyuan TIAN
;
Xuewu LI
;
Zihao ZHANG
;
Zheng XIAO
;
Zhaoyu LIU
;
Haibao WANG
Author Information
1. 解放军总医院海南医院输血科
- Keywords:
Centenarians;
Blood lipid
- From:
Chinese Journal of Geriatrics
2019;38(6):687-690
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of serum lipid levels in centenarians in Hainan province.Methods A total of 899 centenarians were enrolled.Fasting venous blood samples were collected,and serum levels of total cholesterol (TC),triglyceride (TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol (HDL-C),apolipoprotein A-1 (Apo A1),apolipoprotein B(Apo B) and lipoprotein (a) [Lp (a)] were determined.Characteristics of serum lipid levels in centenarians with different age and gender were analyzed.Results The ratio of male to female in this study was 1 ∶ 4,101 years of age comprised the largest proportion(20.4 ％,183 cases),and the highest age was 109 years old for men and 116 years old for women.People aged 102 years had the highest levels of TC,TG,LDL-C and Apo B,and also had the lowest levels of HDL-C and Apo A1.Serum levels of TC and LDL-C reached the peak at the age of 102 years and showed downward trends year by year.Serum levels of TC,TG,LDL-C,Apo A1 and Apo B were lower in males than in females(P＜0.01),and HDL-C had no significant difference between males and females(P ＞0.05).The detection rates for abnormal serum lipid levels were higher in females than in males(P＜0.01).Serum Lp(a) level was higher in females than in males.Conclusions Serum lipid levels show a peak expression at a certain age in centenarians of Hainan,and the types and ratio of abnormal blood lipids are higher in female centenarians than in male centenarians.
