Safety of Propofol combined with Fentanyl in intravenous anesthesia for endoscopic retrograde cholangiopancreatography in elderly patients
10.3760/cma.j.issn.0254-9026.2019.06.015
- VernacularTitle:丙泊酚联合芬太尼静脉麻醉对高龄患者经内镜逆行胰胆管造影术治疗的安全性
- Author:
Jihua SHI
1
;
Xiaoyun QIN
;
Rui GANG
;
Haimeng CUI
;
Hai LI
;
Qingfeng LUO
Author Information
1. 北京医院消化内科国家老年医学中心 100730
- Keywords:
Cholangiopancreatography,endoscopic retrograde;
Choledocholithiasis;
Propofol
- From:
Chinese Journal of Geriatrics
2019;38(6):658-661
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety of Propofol combined with Fentanyl in intravenous anesthesia for endoscopic retrograde cholangiopancreatography(ERCP)in elderly patients.Methods The clinical data of 63 elderly patients aged ≥80 years with common bile duct stones who underwent ERCP in digestive endoscopy center of our hospital were retrospectively analyzed.All the patients were divided into Propofol combined with Fentanyl anesthesia group(group A,n =41)and midazolam combined with Fentanyl anesthesia group(group B,n=22).The changes of blood pressure,heart rate and blood oxygen saturation(SpO2),and postoperative complications were compared between the two groups.Results The incidence of hypotension was higher in Propofol combined with Fentanyl anesthesia group than in midazolam combined with Fentanyl anesthesia group(24.4 ％ vs.0.0％,x2=4.683,P =0.030),but the incidence of SpO2 ＜ 90 ％ in midazolam combined with fentanyl anesthesia group was significantly increased(22.7％ vs.0.0％,x2 =7.250,P =0.007).There was no statistically significant difference in the incidence of anesthesia-related complications (39.0％ vs.36.4％,x2 =0.043,P =0.836) and postoperative complications (4.9 ％ vs.4.5 ％,x2 =0.003,P =0.953) between the two groups.Conclusions For elderly patients with common bile duct stones,intravenous anesthesia with Propofol and Fentanyl during ERCP is safe,and blood pressure changes need to be closely monitored.
