Hot spots and difficult issues in treatment of chronic hepatitis B
10.3760/cma.j.issn.1674-2397.2019.03.015
- VernacularTitle:慢性乙型肝炎治疗难点及热点研究进展
- Author:
Feiyan WEI
1
;
Liaoyun ZHANG
Author Information
1. 山西医科大学第一临床医学院
- Keywords:
Chronic hepatitis B;
Antiviral agents;
Recovery
- From:
Chinese Journal of Clinical Infectious Diseases
2019;12(3):236-240
- CountryChina
- Language:Chinese
-
Abstract:
Chronic hepatitis B (CHB) is a serious disease threatening the health and even life of people, at present antiviral therapy is the key approach to alter the disease outcome.The treatment objectives are to maximize the long-term inhibition of viral replication ; to reduce the inflammatory necrosis of hepatocytes and hepatic fibrosis ; to decompensate the cirrhosis ; to avoid the occurrence of liver failure , hepatocellular carcinoma and other complications ; thereby to improve the quality of life and prolong the survival of patients.The clinical cure should be pursued as far as possible ; however, most of CHB patients can not meet the standard of drug withdrawal and achieve clinical cure.This article reviews the current hot spots and difficult issues in the treatment of CHB.
