Characteristics of 99 Tcm-MDP planar and SPECT/CT imaging in polyostotic bone fibrous dysplasia
10.3760/cma.j.issn.2095-2848.2019.07.004
- VernacularTitle:多骨型骨纤维异常增殖症99Tcm-MDP平面显像与SPECT/CT显像的图像特征
- Author:
Jiqin YANG
1
;
Yanmei LI
;
Fengkui WANG
;
Rong WANG
;
Ying WANG
;
Qian ZHAO
;
Juan LI
Author Information
1. 宁夏医科大学总医院核医学科
- Keywords:
Fibrous dysplasia;
polyostotic;
Tomography;
emission-computed;
single-photon;
Tomography;
X-ray computed;
Technetium Tc 99m
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2019;39(7):400-402
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the image characteristics of whole-body bone planar scan and SPECT/CT imaging in patients with polyostotic bone fibrous dysplasia ( PFD) . Methods Twenty-three pa-tients with PFD (12 males, 11 females, age: 10-77(31.4±3.4) years) between June 2007 and March 2017 were enrolled. Twenty-one patients were confirmed pathologically and 2 was diagnosed by follow-up re-sults. The images of 99Tcm-methylene diphosphonate (MDP) whole-body bone scan and SPECT/CT imaging were retrospectively analyzed. Results Bone involvement in the extremities was the most common and lesions in the lower and right limbs were more than those in the upper and left limbs. Lesions were frequently unilat-erally on whole-body bone planar images in 18 of the other 23 patients ( 78. 3％) . Among them, 15/16 with limb lesions showed no bone deformation in limbs, while the enlargement and deformity were more common in the skull, ribs and pelvis. Vertebral involvement was found in 7 of 23 patients (30.4％), and the hand and foot bone involvement was found in 6 of 23 patients (26.1％). Most lesions (96.9％, 248/256) presented high or mod-erate abnormal uptake, which distributed in a stripe shape in the extremities, ribs and skull. On SPECT/CT ima-ges, the ground glass, vegetable sponge and mixed lesions showed higher uptake compared with the cystic le-sions. Conclusions The PFD has certain characteristics on whole-body bone scan. SPECT/CT imaging can reflect pathological, blood flow and metabolic changes of PFD.
