Changes of local microenvironment in the evolution of intrahepatic cholelithiasis to intrahepatic cholangiocarcinoma
10.3760/cma.j.issn.1007-8118.2019.07.020
- VernacularTitle:肝内胆管结石演变为肝内胆管癌胆管局部微环境的变化
- Author:
Weixuan XIE
1
;
Kunlun LUO
Author Information
1. 安徽医科大学无锡临床学院
- Keywords:
Biliary duct neoplasms;
Tumor microenvironment;
Intrahepatic cholelithiasis;
Intrahepatic cholangiocarcinoma
- From:
Chinese Journal of Hepatobiliary Surgery
2019;25(7):553-556
- CountryChina
- Language:Chinese
-
Abstract:
Hepatolithiasis is a very common hepatobiliary disease in Asia. Recurrent hepatolithiasis frequently lead to incidence of intrahepatic cholangiocarcinoma. The associated intrahepatic cholangiocarci-noma is generally hidden and often covered up by the related clinical symptoms caused by stones, which can easily lead to missed the best time of diagnosisand treatment. This paper mainly showed the diseases of intra-hepatic cholangiocarcinoma associated with intrahepatic cholelithiasis, and expounded the changes of local microenvironment of bile duct tissue from intrahepatic cholelithiasis to intrahepatic cholangiocarcinoma. The purpose of this study is to look for the risk factors related to the development of intrahepatic cholelithiasis to intrahepatic cholangiocarcinoma and to provide a new research direction for the clinical treatment of intrahe-patic cholangiocarcinoma.
